Post Doctoral Researcher in Molecular Mechanisms of Genetic Kidney Disorders

UHN is Canada’s #1 hospital and the world’s #1 publicly funded hospital. With 10 sites and more than 44,000 TeamUHN members, UHN consists of Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre, Toronto Rehabilitation Institute, The Michener Institute of Education and West Park Healthcare Centre. As Canada's top research hospital, the scope of biomedical research and complexity of cases at UHN have made it a national and international source for discovery, education and patient care. UHN has the largest hospital-based research program in Canada, with major research in neurosciences, cardiology, transplantation, oncology, surgical innovation, infectious diseases, genomic medicine and rehabilitation medicine. UHN is a research hospital affiliated with the University of Toronto.

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The Barua lab is seeking an enthusiastic, highly motivated, organized individual with exceptional interpersonal skills for a two-year, potentially extendable, full-time postdoctoral position. The laboratory of Dr. Moumita Barua investigates molecular mechanisms underlying genetic kidney disorders including Alport syndrome, congenital abnormalities of the kidney and urinary tract and Joubert syndrome. The laboratory is located in the vibrant research environment within the MaRS Discovery District attached to Toronto General Hospital and is supported by peer reviewed (CIHR, Kidney Foundation of Canada) and philanthropic grants.

Dr. Moumita Barua is a clinician scientist at University Health Network, Senior Scientist at Toronto General Research Institute and an Associate Professor of Medicine at the University of Toronto. Her mission is to improve diagnostics and clinical outcomes in patients with kidney diseases.

The starting point of the Barua research program is to perform genetic studies in adults with kidney disease using patient and population based cohorts. The human genetic discoveries prioritize clinically relevant models to study kidney disease mechanisms in the lab. The overall objective is to advance preclinical development of novel molecular targets and therapeutics. The 3 main projects in the lab are:

1. Genome-wide association studies of kidney traits

2. Pax2 mediates kidney repair/regeneration - enthusiasm to work with mouse models is an asset

3. Mechanisms in Alport syndrome - enthusiasm to work with mouse models is again an asset

Duties

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