Postdoctoral Researcher

UHN is Canada’s #1 hospital and the world’s #1 publicly funded hospital. With 10 sites and more than 44,000 TeamUHN members, UHN consists of Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre, Toronto Rehabilitation Institute, The Michener Institute of Education and West Park Healthcare Centre. As Canada's top research hospital, the scope of biomedical research and complexity of cases at UHN have made it a national and international source for discovery, education and patient care. UHN has the largest hospital-based research program in Canada, with major research in neurosciences, cardiology, transplantation, oncology, surgical innovation, infectious diseases, genomic medicine and rehabilitation medicine. UHN is a research hospital affiliated with the University of Toronto.

UHN’s vision is to build A Healthier World and it’s only because of the talented and dedicated people who work here that we are continually bringing that vision closer to reality.

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Position Summary

Our lab is a multidisciplinary research program based at the Princess Margaret Cancer Centre (UHN) and closely integrated with the Structural Genomics Consortium (SGC). We operate at the intersection of clinical oncology, experimental biology, and computational genomics, with a focus on decoding chromatin architecture and epigenetic regulation in cancer.

Our work combines 3D genome mapping, functional epigenomics, and multi-omic integration to understand tumor heterogeneity and identify clinically actionable regulatory mechanisms. A central goal of the lab is to translate epigenomic insights into precision oncology strategies, including biomarker development and epigenome-informed therapeutic approaches.

We are seeking a highly motivated Postdoctoral Fellow to lead experimental efforts focused on 3D genome organization in cancer. The successful candidate will drive projects integrating chromatin architecture with transcriptional and regulatory landscapes, using a combination of bulk, single-cell, and spatial epigenomics approaches. The role includes substantial opportunity to develop independent research directions, contribute to high-impact publications, and engage in translational research aligned with precision medicine.

This is an ideal position for candidates interested in working at the interface of experimental and computational epigenomics, within a collaborative and high-impact research environment.

Duties

In addition to working alongside some of the most talented and inspiring healthcare professionals in the world, UHN offers a wide range of benefits, programs and perks. It is the comprehensiveness of these offerings that makes it a differentiating factor, allowing you to find value where it matters most to you, now and throughout your career at UHN.

UHN uses email to communicate with selected candidates. Please ensure you check your email regularly.

Please be advised that a Criminal Record Check may be required of the successful candidate. Should it be determined that any information provided by a candidate be misleading, inaccurate or incorrect, UHN reserves the right to discontinue with the consideration of their application.

UHN is an equal opportunity employer committed to an inclusive recruitment process and workplace. Requests for accommodation can be made at any stage of the recruitment process. Applicants need to make their requirements known.

We thank all applicants for their interest, however, only those selected for further consideration will be contacted.