Postdoctoral Researcher in Mechanisms of Genetic Kidney Disorders

UHN is Canada’s #1 hospital and the world’s #1 publicly funded hospital. With 10 sites and more than 44,000 TeamUHN members, UHN consists of Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre, Toronto Rehabilitation Institute, The Michener Institute of Education and West Park Healthcare Centre. As Canada's top research hospital, the scope of biomedical research and complexity of cases at UHN have made it a national and international source for discovery, education and patient care. UHN has the largest hospital-based research program in Canada, with major research in neurosciences, cardiology, transplantation, oncology, surgical innovation, infectious diseases, genomic medicine and rehabilitation medicine. UHN is a research hospital affiliated with the University of Toronto.

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The Barua Lab is seeking up to 3 highly motivated Postdoctoral Research Fellows for full-time, two-year positions at the University Health Network (UHN). Applicants should be in the top 5% of candidates within their field, with multiple high-impact research outputs and high potential for broad impact. Those with research experience collaborating with industry partners and/or commercialization experience are preferred.

Successful applicants will join the laboratory of Dr. Moumita Barua. The 2 major project subtypes include human omics research utilizing large cohorts like the UK Biobank and All of Us; or mechanistic projects exploring genetic kidney disorders including Alport syndrome, congenital anomalies of the kidney and urinary tract (CAKUT), and Joubert syndrome.

The laboratory is located in the research tower attached to Toronto General Hospital and is supported by peer-reviewed funding (CIHR, Kidney Foundation of Canada) and philanthropic awards.

Dr. Moumita Barua is a Clinician Scientist at the University Health Network (UHN), Senior Scientist at the Toronto General Hospital Research Institute, and Associate Professor of Medicine at the University of Toronto. Her research program aims to improve diagnostics and clinical outcomes for individuals living with kidney disease.

The Barua Lab integrates human genetics, molecular biology, and preclinical modeling to elucidate disease mechanisms and identify therapeutic targets. Genetic discoveries from patient and population cohorts guide the development of clinically relevant models in the lab. Major ongoing projects include: Genome-wide and other omic association studies of kidney traits, Pax2 mediated kidney repair and regeneration, and Mechanistic studies in genetic kidney disease models including for Alport syndrome, CAKUT and Joubert syndrome.

Duties

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Please be advised that a Criminal Record Check may be required of the successful candidate. Should it be determined that any information provided by a candidate be misleading, inaccurate or incorrect, UHN reserves the right to discontinue with the consideration of their application.

UHN is an equal opportunity employer committed to an inclusive recruitment process and workplace. Requests for accommodation can be made at any stage of the recruitment process. Applicants need to make their requirements known.

We thank all applicants for their interest, however, only those selected for further consideration will be contacted.